Ellis and Thatcher Grey This is a marriage that scarred people for life. Alex and April Demon Spawn and the Virgin Surgeon don't mix. George and Meredith These two weren't technically a couple, but their one night of impossibly awkward, incompatible sex is enough to earn them a spot in the Hall of Shame. Owen — whose marriage to Cristina ended because she want kids — had known that all along. Plus, I don't care who you are: Don't go home-wrecking Callie Torres.30. Cristina and Burke It's probably controversial to rank one of the show's cornerstone couples so far down on this list.Plus, Meredith crying mid-sex — but convincing George to keep going anyway? But Emma mentioning it again was immutable proof that she not was, in fact, Cristina.33. If I were ranking on the hotness of on-call room hookups alone, or solely focusing on who had the most intense professional chemistry in the operating room, Cristina and Burke would be a top-five couple.It was always going to end badly, but even by standards, a complete mental break from reality followed by a suicide attempt is a pretty rotten way for things to wrap up.27.

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Looking back on my own writing this year, I found myself writing far too many obituaries — we lost too many talented people in 2007, and it’s tough to sum up the life’s work of an artist you admire in two or three paragraphs punched out on deadline — but I also found they led to some of my most passionate, and most warmly received items.

(Credit here properly belongs to those who inspired me.) I also got worked up writing about such issues as free expression, the hijacking of pop culture for partisan political purposes, and the war on film critics, all of which are, of course, linked.

We've all been there, but I'm no Arizona fan — believe me, I'll get into that soon — but even I admit she deserved better than the whiny mess wrought by her weeks-long hookup with Leah, who took clingy to new heights. Bailey and Tucker It was a bummer to see Bailey go from the happy, smug Married to sad, smothered Married. But the criteria I'm relying on here is the way Cristina has described their relationship in hindsight. One day I was Cristina Yang, and then suddenly I was lying for him, and jeopardizing my career, and agreeing to be married and wearing a ring, and being a bride.

Her husband used their son to try to control Bailey's career, and you have to be a pretty twisted son-of-a-bitch to threaten Miranda Bailey.35. Until I was standing there in a wedding dress with no eyebrows, and I wasn't Cristina Yang anymore." Case closed.28.

At least one half of each couple had to be a member of the Seattle Grace/Mercy West/Sloan-Grey Memorial Hospital staff — so as adorable as George O'Malley's parents were, they're sadly disqualified. Stark with these names, you have my utmost respect. Alex and Olivia/George and Olivia (tie) Olivia the Scrub Nurse was basically just a walking plot device: first she's spreading syphilis around the hospital, next she's getting fired and tipping Derek off about the Chief's erratic behavior in season seven. She was the sort of girlfriend who sent you off to work with homemade banana bread and who took your psychotic coworkers in stride. Izzie and George This relationship was, for both the viewers and the characters themselves, a prime example of "Be careful what you wish for." Izzie and George should've been sweet and funny and, like, on the fast track to having two little kids who would dress up as doctors on Halloween.

Now let's get to it.'s is a show that has ever jumped the shark, but I do know that Alex listening in to Izzie having "sex" with the ghost (or hallucination or whatever) of Denny Duquette was the moment where many long-time viewers gave up on the series. It wasn't bad enough to permanently mar the memory of Izzie and Not Ghost Denny, but it really wasn't good.45. She and George had a cute moment or two though, and she'd likely rank higher on this list if she'd had character traits beyond "competent nurse" and "seems very nice."39. She was Owen's best attempt at Bright and Shiny, and she had every right to be devastated when he dumped her for reiterating that she wanted kids and would want to stay home with them. The complete absence of sexual chemistry in their relationship (which they apparently didn't notice before they embarked on it, but to be fair, viewers didn't really notice either) was their eventual undoing — but not before it was played for some really solid laughs.I do think they loved each other, but then changed in opposite directions.I know that crossover episode where the two of them are crammed into a booth with college friends, laughing and singing and enjoying one another.""much of Teddy and Owen, but we're consistently reminded that they have "a past." I am fine not seeing it.25.Alex and Lucy So, at one point, Alex starts dating this new OB, Lucy. But, as Perkins points out, "You fall for men who aren't available — engaged, only in town for a few weeks ... You deserve more." It's a fair point, but who wants to date the man who both sees and calls you on your shit? Catherine Avery and the Chief Catherine Avery doesn't strike me as the sort of woman you have a relationship with; she strikes me as the sort of woman who sweeps you up.He is such a lovely young man and I love him for that. Daughter of dentist Arthur Allen and Pulitzer-prize nominated Vivan Ayers ( artist, poet, playwright, and publisher).